https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Ganaxolone: a new treatment for neonatal seizures https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31504 A agonist neurosteroid, as a novel neonatal therapy. We discuss evidence that ganaxolone can provide both seizure control and neuroprotection with a high safety profile when administered early following birth-related hypoxia, and show evidence that it is likely to prevent or reduce the incidence of the enduring disabilities associated with preterm birth, cerebral palsy, and epilepsy. We suggest that ganaxolone is an ideal anti-seizure treatment because it can be safely used prospectively, with minimal or no adverse effects on the neonatal brain.]]> Wed 15 Dec 2021 16:09:15 AEDT ]]> Neuroactive steroids in pregnancy: key regulatory and protective roles in the foetal brain https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16519 Sat 24 Mar 2018 08:01:21 AEDT ]]>